J Korean Assoc Oral Maxillofac Surg 2017; 43(5): 288~298
Three-dimensional printing for craniomaxillofacial regeneration
Laura Gaviria, Joseph J. Pearson, Sergio A. Montelongo, Teja Guda, Joo L. Ong
Department of Biomedical Engineering, College of Engineering, The University of Texas at San Antonio, San Antonio, TX, USA
Joo L. Ong
Department of Biomedical Engineering, College of Engineering, The University of Texas at San Antonio, One UTSA Circle, San Antonio, TX 78249, USA
TEL: +1-210-458-7208 FAX: +1-210-458-5515
E-mail: anson.ong@utsa.edu
ORCID: http://orcid.org/0000-0003-3330-2390
Received August 31, 2017; Accepted September 11, 2017.; Published online October 31, 2017.
© Korean Association of Oral and Maxillofacial Surgeons. All rights reserved.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Craniomaxillofacial injuries produce complex wound environments involving various tissue types and treatment strategies. In a clinical setting, care is taken to properly irrigate and stabilize the injury, while grafts are molded in an attempt to maintain physiological functionality and cosmesis. This often requires multiple surgeries and grafts leading to added discomfort, pain and financial burden. Many of these injuries can lead to disfigurement and resultant loss of system function including mastication, respiration, and articulation, and these can lead to acute and long-term psychological impact on the patient. A main causality of these issues is the lack of an ability to spatially control pre-injury morphology while maintaining shape and function. With the advent of additive manufacturing (three-dimensional printing) and its use in conjunction with biomaterial regenerative strategies and stem cell research, there is an increased potential capacity to alleviate such limitations. This review focuses on the current capabilities of additive manufacturing platforms, completed research and potential for future uses in the treatment of craniomaxillofacial injuries, with an in-depth discussion of regeneration of the periodontal complex and teeth.
Keywords: Three-dimensional printing, Periodontium, Hydroxyapatite, Biomaterials

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