Fig. 2. A. Photomicrograph reveals proliferation of fascicular spindled tumor cells in the subepithelial portion (H&E staining, ×100). B. Higher magnification of tumor cells showing blunted, elongated nuclei and abundant eosinophilic cytoplasm with inconspicuous inflammation (H&E staining, ×200). C. Abundant inflammatory infiltrate associated with mucosal erosion (H&E staining, ×200). D. Tumor cells diffusely positive for desmin (immunohistochemistry staining, ×200). E. Tumor cells diffusely positive for myoD1 (immunohistochemistry staining, ×200). F. Tumor cells multifocally positive for anaplastic lymphoma kinase (immunohistochemistry staining, ×200).
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