Journal of the Korean Association of Oral and Maxillofacial Surgeons : eISSN 2234-5930 / pISSN 2234-7550

Fig. 3.

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Fig. 3. Representative cases of medication-related osteonecrosis of the jaws (MRONJ) from the two groups, non-suspension (A-E) and BP suspension (F-J), showing the bone healing progress of two female patients who received oral alendronate 70 mg/week and developed stage 3 MRONJ on the anterior mandible. In the preoperative panoramic radiographs of both patients (A, F), the yellow arrowheads indicate lesion extension. The immediate postoperative panoramic radiographs of both patients (B, G). The three-month follow-up panoramic radiograph revealed signs of pathologic fracture at the base of the mandible in patients who did not suspend BPs (C, blue arrowheads) compared to patients who suspended BPs three months before surgery (H). The six-month follow-up panoramic radiographs revealed extensive expansion of the recurred lesion in patients who did not suspend BPs (D) compared to the patients who suspended BPs, which showed the bone healing process (I). The one-year follow-up panoramic radiograph of a patient who did not suspend BPs (E) and a patient who suspended BPs revealed good and almost complete bone healing on the left anterior mandible (blue arrowheads) (J).
J Korean Assoc Oral Maxillofac Surg 2023;49:75~85