J Korean Assoc Oral Maxillofac Surg 2019; 45(5): 285~293
Reduction in post extraction waiting period for dental implant patients using plasma rich in growth factors: an in vivo study using cone-beam computed tomography
Varun Arya1, Vijay Laxmy Malhotra2, JK Dayashankara Rao1, Shruti Kirti2, Siddharth Malhotra3, Radhey Shyam Sharma2
1Department of Oral and Maxillofacial Surgery, Faculty of Dental Sciences, SGT University, Gurgaon,
2Department of Dentistry, Shaheed Hasan Khan Mewati (SHKM), Govt. Medical College, Nalhar, Nuh, Mewat,
3Private Clinic, New Delhi, India
Vijay Laxmy Malhotra
Department of Dentistry, Shaheed Hasan Khan Mewati (SHKM), Govt. Medical College, Nalhar, Nuh, Mewat 122107, India
TEL: +91-0124-2255303
E-mail: vijay_laxmy13@yahoo.co.in
ORCID: https://orcid.org/0000-0003-3119-7371
Received August 25, 2018; Revised November 26, 2018; Accepted December 20, 2018.; Published online October 31, 2019.
© The Korean Association of Oral and Maxillofacial Surgeons.. All rights reserved.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Objectives: This study examined the effects of plasma-rich growth factors (PRGF) on accelerating bone regeneration/repair in fresh extraction sockets, and determined the quality and quantity of bone by assessing the bone density using cone-beam computed tomography (CBCT).
Materials and Methods: Twenty patients, who had undergone bilateral extractions, were included in this study. In one extraction socket, PRGF was used and covered with an autologous fibrin plug. Nothing was used in the opposite side extraction socket. Thirteen weeks post extraction, the level of bone regeneration was evaluated on both sides with CBCT.
Results: At the end of the study, the mean bone density according to the Hounsfield units (HU) in the control group and PRGF group was 500.05 HU (type III bone type) and 647.95 HU (type II bone type), respectively.
Conclusion: This study recommends the use of PRGF in post extraction sites to accelerate the rate of bone regeneration and improve the quality of regenerated bone. The technique to process PRGF was simple compared to previously mentioned techniques used for platelet-rich plasma (PRP) preparation. PRP preparation requires a two-cycle centrifugation procedure, leading to a longer processing time.
Keywords: Plasma rich in growth factors, Bone regeneration/repair in fresh extraction sockets, Cone-beam computed tomography, Quality and quantity of bone, Platelet rich plasma

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25 October 2019
Vol. 45
No. 5 pp. 231~299

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