J Korean Assoc Oral Maxillofac Surg 2018; 44(3): 136~139
Angioleiomyoma of the oral cavity: a case report and brief review of the literature
Apostolos Matiakis1, Panagiotis Karakostas2, Achilleia-Maria Pavlou1, Eleftherios Anagnostou3, Athanasios Poulopoulos1
Departments of 1Oral Medicine and Pathology and 2Preventive Dentistry, Periodontology and Implant Biology, School of Dentistry, Aristotle University of Thessaloniki, Thessaloniki, 3Pathologist, Thessaloniki, Greece
Apostolos Matiakis
Department of Oral Medicine and Pathology, School of Dentistry, Aristotle University of Thessaloniki, 93 Tsimiski str., Thessaloniki 54622, Greece
TEL: +30-2310-236207 FAX: +30-2310-236207
E-mail: amatiakis@dent.auth.gr
ORCID: https://orcid.org/0000-0002-9314-3531
Received August 16, 2017; Revised November 6, 2017; Accepted November 20, 2017.; Published online June 30, 2018.
© Korean Association of Oral and Maxillofacial Surgeons. All rights reserved.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
This study presents a case of an oral angioleiomyoma along with its clinical diagnostic approach and laboratory confirmation. The differential diagnosis, especially from angioleiomyosarcoma, is also included. A 51-year-old patient presented with a tumor-like lesion on his upper labial mucosa. The clinical examination revealed a benign lesion that was surgically removed. Histopathological and immunohistochemical examinations confirmed the diagnosis of an oral angioleiomyoma. The post-surgical period was uneventful. No recurrence had occurred after a year of follow-up surveillance. Oral angioleiomyoma is a very rarely occurring oral lesion. Clinically, it may mimic some benign lesions, including fibroma, pyogenic granuloma or minor salivary gland tumor. Surgical excision is the treatment of choice. Histological and immunohistochemical examination can confirm the diagnosis. The differential diagnosis is crucial to rule out angioleiomyosarcoma.
Keywords: Oral angioleiomyoma, Oral vascular leiomyoma, Oral leiomyoma

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