J Korean Assoc Oral Maxillofac Surg 2018; 44(3): 107~111
Retrospective clinical study of multiple keratocystic odontogenic tumors in non-syndromic patients
Dae-Seok Hwang1, Yun-Ho Kim1, Uk-Kyu Kim1, Mi-Heon Ryu2, Gyoo-Cheon Kim2
1Department of Oral and Maxillofacial Surgery, School of Dentistry, Pusan National University,
2Institute of Translational Dental Sciences, Pusan National University, Yangsan, Korea
Yun-Ho Kim
Department of Oral and Maxillofacial Surgery, Pusan National University Dental Hospital, 20 Geumo-ro, Mulgeum-eup, Yangsan 50612, Korea
TEL: +82-55-360-5100 FAX: +82-55-360-5104
E-mail: stention@naver.com
ORCID: https://orcid.org/0000-0002-3533-6693
Received December 11, 2017; Revised February 7, 2018; Accepted February 12, 2018.; Published online June 30, 2018.
© Korean Association of Oral and Maxillofacial Surgeons. All rights reserved.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Objectives: A keratocystic odontogenic tumor (KOT) is a type of odontogenic tumor that mainly occurs in the posterior mandible. Most KOTs appear as solitary lesions; however, they sometimes occur as multiple cysts. This study analyzed the clinical features of multiple KOTs.
Materials and Methods: The participants were diagnosed with KOT by biopsy with multiple surgical sites, and were patients at the Pusan National University Hospital and the Pusan National University Dental Hospital from January 1, 2005 to March 31, 2016. Charts, records, images and other findings were reviewed.
Results: A total of 31 operations were conducted in 17 patients. The mean patient age was 28.4±20.1 years. Multiple KOTs were found to occur at a young age (P<0.01). The predominant sites were in the posterior mandible (28.6%). Most cases of multiple lesions appeared in both the upper and lower jaw, and 40.3% of lesions were associated with unerupted and impacted teeth. The overall recurrence rate measured by operation site was 10.4% (8/77 sites). No patients were associated with nevoid basal cell carcinoma syndrome.
Conclusion: The pure recurrence rate was lower than estimated, but there was a higher possibility of secondary lesions regardless of the previous operation site; therefore, long-term follow-up is necessary.
Keywords: Keratocystic odontogenic tumor, Odontogenic keratocyst, Odontogenic cyst, Keratocyst

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31 December 2018
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