J Korean Assoc Oral Maxillofac Surg 2017; 43(3): 160~165
Platelet rich fibrin in the management of established dry socket
Srinivas Chakravarthi
Department of Oral and Maxillofacial Surgery, Sibar Institute of Dental Sciences, Guntur, India
Srinivas Chakravarthi
Department of Oral and Maxillofacial Surgery, Sibar Institute of Dental Sciences, Takkellapadu, Guntur 522509, Andhra Pradesh, India
TEL: +91-866-2439127 FAX: +91-863-2292139 E-mail: drsrinivaschakravarthi@gmail.com ORCID: http://orcid.org/0000-0003-1545-5748
Received October 19, 2016; Revised December 22, 2016; Accepted January 26, 2017.; Published online June 30, 2017.
© Korean Association of Oral and Maxillofacial Surgeons. All rights reserved.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
 Abstract
Objectives: Dry socket may occur secondary to the removal of any tooth. However, most dry socket cases develop in the third molar region. Dry socket is multifactorial in nature and has been treated using various modalities with varying success rates. This study assessed the efficacy of platelet rich fibrin (PRF) in established dry socket.
Materials and Methods: Ten patients of either sex aged from 41 to 64 years with established dry socket according to established criteria were treated using PRF. Evaluation was performed by observing the reduction of pain using visual analogue scale, analgesic tablet use over the follow-up period, and healing parameters.
Results: Pain was reduced on the first day in all patients with decreased analgesic use. Pain was drastically reduced during follow-up on the first, second, third, and seventh days with a fall in pain score of 0 to 1 after the first day alone. The pain scores of all patients decreased to 1 by the first day except in one patient, and the scores decreased to 0 in all patients after 48 hours. Total analgesic intake ranged from 2 to 6 tablets (aceclofenac 100 mg per tablet) over the follow-up period of 7 days. Healing was satisfactory in all patients by the end of the seventh day.
Conclusion: PRF showed early pain reduction in established dry socket with minimal analgesic intake. No patients had allergic reactions to PRF as it is derived from the patient’s own blood. PRF showed good wound healing. Our study suggests that PRF should be considered as a treatment modality for established dry socket.
Keywords: Osteogenesis, Tooth extraction, Tooth impaction, Wound Healing, Pain reduction


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